Hi PhotoWebber,
There are 2 parameters that you can set within the JPEG compression.
- Quality setting: In most programms, you can set between 1 and 100- worst to best. This is only an arbitrary scale and tells nothing about the final file size. Depending on your photos and usage, value between 50 and 100 could be set. However if you are quality conscious, maybe values > 75 should be considered. As harddrives are pretty inexpensive nowadays and as a quality freak

personally I rarely go below 90.
- The so called chroma subsampling. Possible settings are 4:4:4, 4:2:2 etc...as stated in my last post. It can help reducing the file size tremendously. There is a good article in Wikipedia:
http://en.wikipedia.org/wiki/Chroma_subsampling
Chroma subsampling compresses small areas of colours mostly without noticeable loss of perceived image quality. The reason why PhotoPerfect uses 4:2:0 as standard is very simple. It is the standard used in most JPEG and video compressions

Historically this rate produces a good compromise between (small) file size and "perceived" quality, especially for web usage. Perceived does not means that there is no flaws. It just means that most people would not see it. (The delta preview on contrary shows you all possible degradations.) Besides if your display cannot show you the flaws, there is no need to increase the file size just to reduce them. What you don't know won't hurt you
However nowadays with huge technical progresses in displays, cameras, storage space etc..., IMO there is no more reason against the usage of 4:4:4 and 97 quality setting...but that's just me
