Hi,
As default PhotoPerfect Express always starts opening the last used folder. This is a setting, which has been asked for by the majority of our users.
If that folder has been removed or renamed, PPE will automatically revert back to the desktop, as the rendering engine requires at least 1 image of a supported formats (JPEG, PNG, TIFF). On a few systems this might cause the behaviour you described. Please find below a new build, which can fix this:
PPE Build 80
This version will revert to the 'Sample Images' folder instead.
Best regards
Hoang-Tran